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    🦵 Leg Cramps: Causes, Prevention, and Natural Remedies

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      How to Reverse It and Why Sugar Is NOT the Problem

      Tom Brimeyer by Tom Brimeyer
      16/04/2025
      in Blog
      How to Reverse It and Why Sugar Is NOT the Problem

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      Hypothyroidism and diabetes tend to go hand-in-hand.

      Anyone who is diabetic will functionally become hypothyroid because their cells become blocked from using thyroid hormone efficiently.

      And anyone who is hypothyroid will have a tendency toward becoming pre-diabetic and eventually diabetic because of how their body compensates for their thyroid condition.

      In this article, which is based largely on the work of Dr. Raymond Peat, I’m going to show you how you can prevent this from happening, but in order for this to all make sense…

      …you first have to understand the truth about diabetes and the vicious cycle that causes it.

      Today, diabetes (along with a list of other health conditions) is blamed directly on the over-consumption of sugar. It’s oftentimes referred to as the “Sugar Disease”.

      And for those without a proper understanding of how the body works, this might make sense.

      When a diabetic consumes large amounts of glucose, their blood sugar rises.

      And a chronic rise in blood sugar can lead to various health complications.

      But, let me ask you this…

      Imagine you have a clogged sink drain while your water is running.

      Graphic of an over flowing sinkGraphic of an over flowing sink

      As the water level continues to get higher and higher do you curse the water and blame it for clogging your sink?

      No, that wouldn’t make any sense.

      Would turning off the water and letting the water sit there solve your problem? Of course not.

      We all know the underlying problem that you have to fix is the clog itself.

      Then why are so many people guilty of taking this very approach with diabetes today?

      Diabetes is NOT a Sugar Disease

      Let’s get one thing straight…

      Diabetes is not a disease “caused” by sugar.

      You require insulin to deliver glucose to your cells.

      This is why in type 2 diabetes, insulin injections are prescribed to treat the condition while doing nothing to solve the problem.

      Diabetes is a dysfunction within your body that prevents your cells from using glucose.

      So, just as the case with your clogged sink, blaming the water, or in this case sugar, doesn’t make much sense.

      If the underlying problem is that your cells are clogged, preventing you from being able to use glucose, then you can’t blame glucose as the problem.

      And if you think that turning off the water, or removing sugar from your diet is the solution then you’re in for a big surprise as well.

      Removing sugars and carbohydrates from your diet as a band-aid approach to forcing your blood sugar lower also fails to fix the underlying problem.

      Regardless of what your blood sugar levels are, your cells are still clogged and the underlying problem still exists.

      In fact, using a low-carb diet to manage your diabetes is actually quite dangerous in itself.

      With the increasing popularity of low-carb diets today, I’ve been seeing a higher prevalence of diabetes and especially pre-diabetes in my clients.

      For example, I recently consulted with a couple who both followed a low carbohydrate diet, one for 2 years, and one for less, while both developed thyroid issues.

      (Note: Low-carb diets are well known to suppress thyroid function as discussed in this article on low carb thyroid dangers.)

      But they became very concerned when their latest trip to their doctor uncovered that both had also become pre-diabetic with elevated blood sugar.

      They didn’t understand how their blood sugar could possibly be high when they ate so few carbohydrates and absolutely no sugar.

      This is far more common than you think.

      And I’ll explain how this happens in just a second.

      The important thing to understand here is that diabetes is caused by a dysfunction within your body preventing your cells from using glucose.

      And blaming sugar and trying to avoid all sugars is NOT how you fix the underlying problem.

      How Hypothyroidism Leads to Diabetes

      It all boils down to what’s called the Randle Cycle.

      In a nutshell, the Randle Cycle is a mechanism by which the presence of large amounts of free fatty-acids (or fats) in your bloodstream compete with the sugar in your bloodstream and block your cells from being able to use or metabolize your blood sugar.

      So, it should be no surprise to learn that diabetics have high levels of circulating free-fatty acids in their blood.

      And as mentioned previously, if you can’t get sugar to your cells then you won’t be able to use thyroid hormone efficiently.

      So, how does this occur in hypothyroidism?

      It’s well known that in hypothyroidism, your liver loses its ability to store and release its storage form of sugar, glycogen.

      (Note: This is covered in detail in this article on “How to Heal Your Thyroid By Healing Your Liver”.)

      Graphic of the 3 liver fixes fo thyroid healthGraphic of the 3 liver fixes fo thyroid health

      And it’s this liver glycogen or stored sugar that is supposed to be keeping your blood sugar stable, especially between meals.

      This is why hypothyroidism sufferers lose the ability to properly regulate their blood sugar and instead are forced to compensate by over-producing stress hormones instead.

      Those stress hormones, adrenaline and cortisol, are hormones of survival.

      Consider the fact that your brain is the largest consumer of sugar in your body.

      And it requires a huge amount of sugar to function.

      If your blood sugar continued to drop too low then your brain would not be able to function, you would lose consciousness, and you wouldn’t be able to recover.

      Graphic of unconscious woman on a benchGraphic of unconscious woman on a bench

      In other words, life as you know it would be over.

      The primary purpose of these stress hormones is to keep you alive by preventing your blood sugar from dropping too low.

      When you are hypothyroid and your blood sugar drops, your body first secretes the stress hormone adrenaline.

      It does so to stimulate your liver to release its stored glycogen/sugar, which as mentioned a hypothyroid liver can’t store.

      Adrenaline also triggers the release of free fatty-acids from your stored fats into your bloodstream, which we know from the Randle Cycle prevents your cells from being able to use sugar.

      And it’s these free fatty-acids that are responsible for the development of insulin resistance.

      This is well documented through numerous research studies including the following two just as an example:

      Free fatty acids and insulin resistance.
      http://www.ncbi.nlm.nih.gov/pubmed/17285001
      “Dysregulation of free fatty acid metabolism is a key event responsible for insulin resistance and type 2 diabetes. According to the glucose-fatty acid cycle of Randle, preferential oxidation of free fatty acids over glucose plays a major role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. However, other mechanisms are now described to explain the molecular basis of insulin resistance.” “The increase in free fatty acid flux resulting from increased lipolysis secondary to adipose-tissue insulin resistance induces or aggravates insulin resistance in liver and muscle through direct or indirect (from triglyceride deposits) generation of metabolites, altering the insulin signalling pathway. Alleviating the excess of free fatty acids is a target for the treatment of insulin resistance.”

      Interaction between free fatty acids and glucose metabolism.
      http://www.ncbi.nlm.nih.gov/pubmed/12172479
      “Elevated plasma FFA levels have been shown to account for up to 50% of insulin resistance in obese patients with type 2 diabetes mellitus. Lowering of FFAs in these patients or interfering with steps in the pathway through which FFAs cause insulin resistance could be a new and promising approach to treat type 2 diabetes mellitus.”

        If you want to blame diabetes on something, blame it on PUFA.

      Graphic of what foods contain PUFAsGraphic of what foods contain PUFAs

      This is why we recommend avoiding polyunsaturated fats (PUFA) at all costs.

      PUFA oils are generally oils that are liquid at room temperature (olive oil is a slight exception) and are used widely in restaurants, almost all packaged foods, and just about everything you eat.

      Needless to say, much of the fats consumed today are in the form of PUFA.

      And therefore there are high levels of PUFAs stored within your body’s fat stores.

      So, when you are hypothyroid and compensate by secreting large amounts of adrenaline, it results in large amounts of PUFA being released into your bloodstream.

      And as Dr. Raymond Peat points out, these PUFA are responsible for killing insulin producing beta-cells of your pancreas.

      “The antimetabolic and toxic effects of the polyunsaturated fatty acids can account for the “insulin resistance” that characterizes type-2 diabetes, but similar actions in the pancreatic beta-cells can impair or kill those cells, creating a deficiency of insulin, resembling type-1 diabetes.” Dr. Raymond Peat, PhD

      This is also shown through research:

      Long-term exposure of INS-1 rat insulinoma cells to linoleic acid and glucose in vitro affects cell viability and function through mitochondrial-mediated pathways.
      http://www.ncbi.nlm.nih.gov/pubmed/21161439
      “The results of this study indicate that chronic exposure to linoleic acid-induced β-cell dysfunction and apoptosis [cell death]…”

      So, not only do these free fatty-acids cause insulin resistance within your cells, they kill your cells that produce the insulin that you need to deliver glucose to your cells.

      This is a diabetes disaster just waiting to happen.

      And cortisol plays an important role in diabetes as well.

      The primary role of the stress hormone cortisol is to break down protein tissue in your body and to convert that protein into sugar, as a means of preventing your blood sugar from dropping too low.

      And it’s this cycling of adrenaline and cortisol among hypothyroidism sufferers that creates the vicious diabetes cycle.

      Hypothyroidism and the Vicious Diabetes Cycle

      With hypothyroidism we see a continual cycle where your body compensates by secreting large amount of adrenaline followed by large amounts of cortisol.

      As adrenaline rises and releases stored PUFAs into your bloodstream it…

      1. Blocks your cells from metabolizing glucose.
      2. Promotes insulin resistance within your cells.
      3. Kills your insulin producing cells.

      Then cortisol rises and breaks down protein resulting in a surge of glucose, which is blocked from entering your cell and results in…

      1. The production of more adrenaline.
      2. More insulin resistance.
      3. And more death to insulin producing cells.

      This cycling and surging of adrenaline and cortisol is what’s responsible for the development of insulin sensitivity and insulin deficiency.

      Over time your ability to metabolize glucose becomes further and further impaired as your blood sugar continues to rise in an attempt to keep your cells and brain functioning.

      As you can see, the problem actually has little to do with sugar itself…

      …and it has everything to do with PUFA.

      While avoiding PUFA in your diet is extremely important, there are also foods that you should be using that can help protect you from diabetes by boosting your thyroid function.

      Some of those foods can be found in our 3 Food Thyroid-Boosting Daily Protocol.

      3 Food Triple-Thyroid-Boosting Daily Protocol3 Food Triple-Thyroid-Boosting Daily Protocol

      You can down it for free by clicking here.

      Low-Carb Diets May Lower Blood Sugar But Worsen Diabetes

      Graphic showing the dangers of low-carb dietsGraphic showing the dangers of low-carb diets

      Lowering your blood sugar by removing carbohydrates from your diet will never fix the underlying problem of diabetes.

      Sure, you’ll go to your doctor who will monitor your fasting blood sugar and see that it is lower, or even within “normal” range.

      Your blood sugar will likely remain within range for a period of time. But the underlying dysfunction still exists.

      Your cells are still not able to use sugar.

      And you are still for all intents and purposes, diabetic.

      Your brain still requires huge amounts of sugar to function and will get it at any cost.

      It’s pure survival.

      It’s supply and demand.

      In diabetes, if your brain can’t get the sugar it needs (increase in demand) it will force your blood sugar higher (increase in supply) by producing more stress hormones.

      And if it’s the over-production of adrenaline and cortisol that caused the problem to begin with… then forcing your body to produce more of these stress hormones will never solve the problem.

      By removing more and more carbohydrates from your diet, all you’re doing is forcing your body to produce more adrenaline and cortisol to compensate, which only makes your diabetes worse.

      This is why diabetics and hypothyroidism sufferers who follow a low-carb diet long term will see that their blood sugar “stabilizes” initially for a period of time and then begins to increase again no matter how few carbohydrates they consume.

      Just as in the case of my two low-carb clients I mentioned earlier.

      The more carbohydrates they removed from their diet, the more diabetic they became.

      And the more difficult it becomes to reverse.

      How to Reverse Diabetes

      I work with plenty of diabetic clients and it does take time and is not always easy.

      The approach we take with clients and use in our Hypothyroidism Revolution Program is very different than what most are used to.

      But it’s important to understand that the only way to solve the problem of diabetes is to fix the underlying dysfunction that causes it.

      In our case of the clogged sink, we don’t blame the water (sugar) and we don’t just turn the water off (remove carbohydrates from our diet).

      Instead we work to remove the clog (the real underlying problem) itself.

      For starters, we need to overcome your inability to regulate your blood sugar.

      To do this, we use diet to compensate for the liver by eating the right balance of carbohydrates and frequently enough to keep blood sugar regulated.

      We’re essentially using diet to regulate your blood sugar while your liver is unable to do it.

      Then we work to prevent the release of the free fatty-acids into our bloodstream that triggers the Randle Cycle and promotes diabetes.

      Graphic showing the Randle CycleGraphic showing the Randle Cycle

      One way to do this is through the use of vitamin B3 (Niacinamide) which helps inhibit the lipase enzyme that releases free fatty-acids from stored fat.

      Keeping those free fatty-acids out of your bloodstream is essential.

      Then we can use certain carbohydrates therapeutically to help restore your ability to get glucose to your cells and for your cells to use that glucose efficiently.

      For example, consuming more fruits and getting more fructose is known to help improve your cells ability to use glucose.

      Acute fructose administration improves oral glucose tolerance in adults with type 2 diabetes.
      http://www.ncbi.nlm.nih.gov/pubmed/11679451
      “CONCLUSIONS: Low-dose fructose improves the glycemic response to an oral glucose load in adults with type 2 diabetes, and this effect is not a result of stimulation of insulin secretion.”

      Focusing on less grains and starches and more fruits is very effective.

      Yet today, we live in a world where more people have become afraid of healthy carbohydrates.

      Fruit and fructose containing sugars have been shown to prevent diabetes.

      Even orange juice has been shown to be an ideal source of carbohydrates for diabetics.

      So, don’t be afraid of carbohydrates.

      They can actually help save your life.

      Now you know how to support thyroid to reverse diabetesNow you know how to support thyroid to reverse diabetes

      KEY IDEA

      Diabetes isn’t caused by sugar but by cells being unable to use sugar properly. When someone has hypothyroidism, their liver can’t properly store and release sugar, forcing their body to release stress hormones (adrenaline and cortisol). These hormones release harmful polyunsaturated fatty acids (PUFAs) into the bloodstream, which further block cells from using sugar and even kill insulin-producing cells. Low-carb diets may temporarily lower blood sugar but actually make the problem worse by forcing more stress hormone production. Managing diabetes requires eating the right balance of carbohydrates (especially fruits), avoiding PUFAs, and using vitamin B3 to prevent fatty acid release into the bloodstream.

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