NAD+ (Nicotinamide Adenine Dinucleotide) supplements have gained huge popularity for their potential to boost cellular energy, improve metabolism, support healthy aging, and enhance brain function. But with so many brands and formulations available, how do you pick the right one?
This guide breaks down the top NAD+ supplements by quality, formulation, price, and user feedback, so you can find the best fit for your needs.
What is NAD+ and Why Supplement?
NAD+ is a vital coenzyme in every cell that helps convert food into energy, regulates DNA repair, and supports mitochondrial function. NAD+ levels naturally decline with age, which may lead to fatigue, cognitive decline, and metabolic issues. Supplementing with NAD+ precursors like nicotinamide riboside (NR) or NADH can help restore these levels and improve overall wellness.
Key Factors to Consider When Buying NAD+ Supplements:
- Formulation Type: Most supplements use NR or NADH. NR is the most studied and widely recommended for bioavailability.
- Dosage: Typical effective doses range from 250mg to 500mg daily.
- Delivery Method: Liposomal formulas may increase absorption.
- Scientific Evidence: Brands with clinical trials and published research generally offer more reliable products.
- Price: Higher price often means better quality but look for value and transparency.
- Customer Feedback: Real user reviews can reveal effectiveness and side effects.
Comparison Table: Top NAD+ Supplement Brands
| Brand Name | Formulation | Dose per Serving | Capsules per Bottle | Price Range (USD) | Rating (out of 5) | Key Benefits | Buy Now |
|---|---|---|---|---|---|---|---|
| Tru Niagen (ChromaDex) | Nicotinamide Riboside (NR) | 300 mg | 30 | $40 – $60 | 4.7 | Clinically studied, high purity, boosts energy & aging support | Buy on Amazon |
| Elysium Basis | NR + Pterostilbene | 250 mg NR + 50 mg | 60 | $60 – $80 | 4.5 | Research-backed, cognitive & mitochondrial health, premium formula | Buy on Amazon |
| Life Extension NAD+ Cell Regenerator | NR | 300 mg | 30 | $45 – $55 | 4.4 | Cellular repair, steady energy, reputable brand | Buy on Amazon |
| CATA-KOR NAD+ 500mg (Liposomal) | Liposomal NAD+ | 500 mg | 60 | $50 – $70 | 4.3 | Enhanced absorption, user-reported energy & clarity boost | Buy on Amazon |
| NOW Foods NADH | NADH | 10 mg | 60 | $20 – $30 | 4.0 | Affordable, brain & energy metabolism support, mixed reviews | Buy on Amazon |
| Thorne Research ResveraCel | NR + Resveratrol | 250 mg NR + 100 mg | 60 | $70 – $90 | 4.2 | Longevity blend, antioxidant support, trusted quality | Buy on Amazo |
Summary and Recommendations:
- Best Overall: Tru Niagen — Most clinically supported with consistent quality.
- Best Premium Formula: Elysium Basis — Combines NR with antioxidants for extra benefits.
- Best Value: NOW Foods NADH — Affordable entry into NAD+ supplementation.
- Best Absorption: CATA-KOR Liposomal NAD+ — Liposomal delivery for better uptake.
- Best Longevity Focus: Thorne ResveraCel — Combines NAD+ with resveratrol for anti-aging.
FDA Warning and Safety Notes
NAD+ supplements are generally considered safe but are not evaluated or approved by the FDA to diagnose, treat, or prevent any disease. It’s essential to buy from reputable brands and consult your healthcare provider before starting, especially if you’re pregnant, nursing, or have medical conditions.
