Best Supplements for Thyroid Mood Swings, Anxiety, and Depression

Mood swings, anxiety, and depression… up to 60% of thyroid patients will struggle with these problems.

But they don’t have to. Why?

Because there are natural treatments and supplements that can help bring balance to your brain and thyroid at the same time.

Here are 5 science-backed supplements to take for better brain health:  

#1. Creatine

Your brain is an energy hog, accounting for roughly 20% of the body’s total energy usage (1)!

And when you have a sluggish thyroid, that processing power slows way down. 

Creatine steps in to provide your brain (and body) with an immediate source of energy, which means:

Use 5 grams of creatine monohydrate daily. 

#2. Magnesium

Feeling nervous, jittery, or anxious? Try magnesium. 

It’s called the calming mineral for a reason. 

Magnesium improves your stress response, controls neurotransmitters like GABA, and lowers cortisol. 

The result? You’ll be more zen and less frazzled. You’ll also enjoy a slight boost to thyroid function through its impact on iodine uptake.

It also happens to be the case that a staggering 75% of adults don’t get enough magnesium from their diet (2). 

Meaning: 

This is a perfect opportunity for you to take magnesium and feel the difference. 

Use 300 mg of magnesium glycinate or 2,000 mg of magnesium threonate at night before bed.

#3. L-Theanine

Found in green tea, L-theanine promotes relaxation WITHOUT causing drowsiness (3). 

Perfect for thyroid patients who feel wired but tired and unable to sleep. 

Using it before bedtime is best to help promote a more restful sleep and help you hit that coveted 5-6 hours of NREM sleep that you need for optimal thyroid function and brain health. 

Take 100-400 mg of L-theanine 30-40 minutes before “bedtime” to shut off anxiety and increase alpha waves. 

#4. Myo-inositol

This sugar-like compound influences serotonin, GABA, and melatonin, making it beneficial for both mood and sleep. 

But its benefits don’t stop there. 

By impacting intracellular messengers, it helps your cells respond properly to TSH (4). 

This means better thyroid function, a healthier TSH, and more T4 & T3. 

The ideal dose for both thyroid and mood is 600 mg of myo-inositol daily. 

#5. Vitamin D

Vitamin D is more of a hormone than a vitamin, and low levels have been linked to depression, brain fog, and autoimmune disease (5). 

It’s important for everyone, but especially those with autoimmune thyroid disease like Hashimoto’s. 

Remember: up to 90% of all hypothyroidism is caused by this condition!

Regardless of what thyroid condition you have, get your 25-hydroxy vitamin D tested. 

If it’s low, take 2,000 to 5,000 IU of vitamin D3. 

Your thyroid gland affects every cell in your body, especially your brain.

If it’s out of balance, you’ll feel it with changes to your mood, energy, and focus.

But you can take back control with these science-backed supplements. And if you prefer, you can always get them from natural food sources.

Either way, don’t let your thyroid throw off your brain chemistry.

Find my recommended products for each below, and bookmark this in case you need it in the future:

If you are still having trouble getting your mood under control, give T3 a shot.

You can learn more about how to use that thyroid hormone here.